الملف الأكاديمي

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Research Intersets
Qualifications
Experiences
Publications
University Courses Taught
Master and Phd thesis contributions
Projects
Conferences and Workshops
Journals Editor/ Reviewer
Community Service
عربي Dr. Mo'Ath Yaseen Abdallah Alqaraleh
ASSISTANT PROFESSOR
https://www.bau.edu.jo/user/@muath.garalleh
 Major: biology
 Minor: biochemistry and Clinical biochemistry
 muath.garalleh@bau.edu.jo
 0795038456

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I have been working as an Assistant Professor at Al-Balqa Applied University in Jordan since 2024, in the Department of Medical Laboratories within the Faculty of Medical Sciences. My research focuses on investigating the molecular pathways associated with cancer, particularly the impact of nanoparticles, such as silver nanoparticles, on key biological pathways like MAPK and PI3K. I have a specific interest in regulating miRNA gene expression in cancer patients and studying the effects of hormones and chemotherapy on these genes.

I earned my Ph.D. in Clinical Biochemistry from the University of Jordan in 2018, where my dissertation focused on evaluating the pancreatic and antioxidative effects of selected branched amino acids and fatty acids in vivo and in vitro. I also obtained a Master?s degree in Biological Sciences from Mutah University, where my thesis investigated the ability of Moraxella lincolnii bacteria to degrade 3,4-dichlorobenzoic acid under optimal growth conditions.

I have extensive practical experience in laboratory techniques such as polymerase chain reaction (PCR), gel electrophoresis, genetic analysis, and flow cytometry. Additionally, I possess advanced skills in statistical analysis using software like SPSS and GraphPad Prism, which enables me to design and analyze advanced laboratory experiments.

I teach a range of university courses for undergraduate and graduate students, including clinical biochemistry, molecular biology, pathology, and histology. I have also supervised several Master?s theses on topics such as the effect of marine sponge extracts on cancer cells, the impact of nanoparticles on bacteria and cancer cells, and the study of genes associated with chronic diseases such as diabetes and liver disease.

Research Intersets:
My interests focus on the molecular pathways of cancer and the impact of nanoparticles on critical cellular pathways such as MAPK and PI3K in different types of cancer.
My secondary area of interest revolves around the regulation of miRNA expression in cancer patients, with a specific emphasis on the effects of hormones and chemotherapy.

Qualifications
# Degree University Specialization Graduation year
1PHDUniversity of Jordanbiology2017
2MASTER DEGREEMutah universitybiology2011
3BACHELOR'S DEGREEMutah universitybiology2008

Experiences
Academic Experience:
2020 -2023 :assistant professor,Al-Ahliyya Amman University,Jordan.

Administrative Experience:
2025 -Current :Assistant Dean for Planning, Development and Quality Assurance,Al-Balqa Applied University,Jordan.

Publications
1- Investigation of selected MiRNA as potential biomarker in Chronic Myeloid Leukemia patients ,Medicine and Pharmacy Reports, 2026,Vol. -,no. -.
2- Mechanistic Toxicity of Fungal-Derived Silver-Containing Nanoparticles and Biochar: Redox and Inflammatory Responses in Breast and Colorectal Cancer Cells ,Journal of Applied Toxicology , 2026,Vol. -,no. -.
3- Bioactive Constituents and Potential Cytotoxic Activities of Green Microalgae: Desmodesmus spp. from a Jordanian Isolate ,Anti-Cancer Agents in Medicinal Chemistry, 2026,Vol. 26,no. 0.
4- Epigenetic Reactivation of SOCS-3 and Inhibition of ERK1/2 Underlie Thymoquinone-Induced Apoptosis in a Chronic Myeloid Leukemia Xenograft Model ,Medical Principles and Practice, 2026,Vol. -,no. -.
5- Synergistic Anticancer and Antibacterial Activities of Marine Sponge Extracts Combined with Fungal-Synthesized Silver Nanoparticles from Aspergillus flavus ,العوامل المضادة للسرطان في الكيمياء الطبية, 2026,Vol. 26,no. -.
6- Assessment of triglyceride glucose index and triglyceride to HDL cholesterol ratio as markers of insulin resistance defined by the Homeostatic Model Assessment 2 in Middle Eastern adults with excess adiposity ,Medicine and Pharmacy Reports, 2026,Vol. 99,no. 1.
7- Sustained Glipizide Release and Enhanced Hypoglycemia With Nano-Mesoporous SBA-15 in Diabetic Mice ,Journal of Biochemical and Molecular Toxicology, 2026,Vol. 40,no. 3.
8- Ononin synergistically enhances the cytotoxic effect of doxorubicin in MDA-MB-231 triplenegative breast cancer cell line ,Pharmacia, 2026,Vol. 73,no. -.
9- Role of Specific miRNA Expression and Nuclear Kappa B Gene Polymorphism as Potential Diagnostic Markers for Chronic Myeloid Leukemia ,Medical Principles and Practice, 2026,Vol. 35,no. 3.
10- Hematological and Biochemical Predictors of Cancer Diagnosis: An Analytical Study from a Cancer-Enriched Clinical Cohort ,Medical Archives, 2025,Vol. 79,no. 6.
11- Neural Network-Based Cancer Diagnosis from Routine Hematological and Biochemical Data: Performance, Target Leakage, and Clinical Implications ,Acta Informatica Medica, 2025,Vol. 33,no. 4.
12- Co-Loaded Nanoparticles of Empagliflozin and Rutin for Pancreatitis Prevention and Anticancer Activity ,Drug Development Research, 2025,Vol. 86,no. 6.
13- Baicalein Sensitizes Triple Negative Breast Cancer Cells to Cisplatin by Activating Apoptosis ,Natural Product Communications, 2025,Vol. 20,no. 8.
14- Epidemiological Insights into Diabetes, Hypertension, and Heart Disease: Evidence from a Publicly Available Health Dataset ,Medical Archives, 2025,Vol. 79,no. 4.
15- Novel Anticancer Triple Formula Based on Aptamer-Conjugated PEGylated Nanoliposomes ,Technology in Cancer Research & Treatment, 2025,Vol. 24,no. -.
16- Rhoifolin potentiates the anti-cancer activity of doxorubicin in MDA-MB-231 triple-negative breast cancer cells ,Pharmacia, 2025,Vol. 72,no. .
17- Phenotypic Variability and Hematological Characterization of ?0- and ?+-Thalassemia Carriers: A Comparative Study ,Journal of Clinical Medicine Research, 2025,Vol. 17,no. 4.
18- Innovative liposomal coumarin: A promising solution for enhancing soft white cheese quality ,plos one, 2025,Vol. ,no. .
19- Evaluation of the Synergistic Cytotoxicity of Camptothecin with Silver Nanoparticles: Potential Anti-angiogenic, Anti-inflammatory, and Antioxidant Agents ,Jordan Journal of Biological Sciences (JJBS), 2025,Vol. 18,no. 2.
20- Optimized Rutin-incorporating PEGylated Nanoliposomes as a Model with Remarkable Selectivity Against PANC1 and MCF7 Cell Lines ,Anti-Cancer Agents in Medicinal Chemistry, 2025,Vol. 25,no. 12.
21- Therapeutic potential of marine sponges and nanoparticles: A study on siphonochalina siphonella and AgNPs ,Journal of Medicinal and Pharmaceutical Chemistry Research, 2025,Vol. 7,no. 4.
22- Bioactive potency of extracts from Stylissa carteri and Amphimedon chloros with silver nanoparticles against cancer cell lines and pathogenic bacteria ,BIOMEDICAL REPORTS, 2024,Vol. 22,no. 2.
23- The effects of Anchusa azurea methanolic extract on burn wound healing: Histological, antioxidant, and anti-inflammatory evaluation ,Burns, 2024,Vol. 50,no. 7.
24- The combination effects of Vorinostat and Silver Nanoparticles Targeting Angiogenesis, Oxidative Stress, and Inflammation: An in vitro study ,Journal of Medicinal and Chemical Sciences, 2024,Vol. 7,no. 10.
25- Thymoquinone Enhances Apoptosis of K562 Chronic Myeloid Leukemia Cells through Hypomethylation of SHP-1 and Inhibition of JAK/STAT Signaling Pathway ,المستحضرات الصيدلانية, 2023,Vol. 16,no. 6.
26- Fungal-Mediated Silver Nanoparticle and Biochar Synergy against Colorectal Cancer Cells and Pathogenic Bacteria ,Antibiotics, 2023,Vol. 12,no. 3.

University Courses Taught
1- BIOCHEMISTRY.
2- STATISTICAL ANALYSIS.
3- CLINICAL CHEMISTRY.
4- GENETICS.
5- ADVANCED CLINICAL CHEMISTRY.

Master and Phd thesis contributions
Thesis Supervision
Effect of Cinnamon on Pancreatic ?-Cell Function in Type 2 Diabetes Mellitus (T2DM) Rats ,Al-Balqa Applied University,Master Thesis,2026.
Dual Biomarker Strategy Using miRNA-302 and Interleukin- 6 for Early Diagnosis of Chronic Kidney Disease ,Al-Ahliyya Amman University,Master Thesis,2025.
The effect of HDAC Inhibitor and Silver Nanoparticles on selected miRNA in Myelogenous Leukemia cell lines ,Jordan University of Science and Technology,Master Thesis,2025.
Profiling miRNA Panels as Predictive Biomarkers in Chronic Kidney Diseases ,Al-Balqa Applied University,Master Thesis,2025.
Profiling miRNA-21 and Uromodulin as Novel Biomarkers for Early Detection of Chronic Kidney Disease ,Al-Ahliyya Amman University,Master Thesis,2025.

Projects
The Epigenetic changes of Hedgehog/GLI signaling genes targeted by combined Decitabine and Thymoquinone treatment against acute myeloid leukemia ,جامعة البلقاء التطبيقية,2025/11-2027/11.
Differential Expression Of microRNA in Acute Lymphoblastic Leukemia Treated with tyrosine kinase inhibitors ,Scientific Research and Innovation Support Fund,2024/03-2027/03.
The synergistic effect of biochar and biosynthesized silver nanoparticles (AgNPs) on performance of AgNPs against different cancer cells and pathogenic bacteria ,جامعة عمان الاهلية,2022/01-2023/01.

Conferences and Workshops
# Conference/Workshop Name Conference/Workshop Place Conference/Workshop Date
1EU-Jordan Research Day 2026Jordan2026/06
2The First International Conference of Artificial Intelligence in Health SciencesJordan2025/11
3Data Analysis By Python CourseJordan2024/08
4Applied Science Private University Pharmacy Fourth International ConferenceJordan2019/01
5Molecular BiotechnologiesJordan2016/06
6data analysis using SPSSJordan2016/02
7Comprehensive Computer CourseJordan2009/06

Journals Editor/ Reviewer
Editors
Anti-Cancer Agents in Medicinal Chemistry.
Review:
Molecular Medicine Reports.
Jordan Journal of Pharmaceutical Sciences.

Community Service :
Contribution to the organization and support of the Scientific Day activities at the Faculty of Allied Medical Sciences..
Participation in the Scientific Day activities of the Medical Laboratory Sciences Department and contribution to scientific activities and professional development..
Reviewing scientific research for a peer-reviewed journal within Jordan.


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